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INCLUSION CRITERIA

>18 years old

CAP diagnosis at admission or <48h from admission including compatible CXR

CRP>70

May or has required invasive ventilation (do not randomise until intubated)

EXCLUSION CRITERIA




 

Pregnant or breast feeding

On ECMO

HAP/VAP including patients discharged from hospital within last 14 days

Neutropenic (<0.5)

Thrombocytopenic (<30)

ESKD or FSGS diagnosis

Pre-existing sig lung disease involving active TB or cancer

Severe Liver disease (CPS>10 points) or HCC

Severe chronic heart failure (NYHA 3/4)

IgA deficiency

Fluroquinolone in last 2 days prior to randomisation

Previous lung transplant or stem cell transplant in last year

Study Information

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© 2035 by Dr Phil Hopkins

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